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μ-Butyrolactone (GBL) is a colorless hygroscopic water-mixable fluid of low odour. It is 4-carbon lactone the simplest. In humans, GBL acts like a prodrug for α-hydroxybutyric acid (GHB) and as a recreational CNS depressant with effects similar to that of barbiturates; it is used as an intermediate in the production of other chemicals, e.g. methyl-2-pyrrolidone.
How is GBL made?
Extracts of GBL from unadulterated wine samples were found. This finding shows that in some wines GBL is naturally present and can be found in similar products. The detection concentration was about 5 μg/mL and was easily followed by a GC/MS analysis with a simple removal technique. In cheese-flavors, GBL can be found, but in general, the final food is 0.0002% GBL. GBL.
Delhydrogenation of 1,4-butanediol at 180-300 ° C, atmospheric pressure in the presence of copper catalyst, produces α-Butyrolactone industrially.
The return of this process is about 95%. Cleansing takes place by extracting the liquid gas phase.
The oxidation of tetrahydrofuran, such as aqueous sodium bromate, can also be achieved in the laboratory. GABA uses the Sandmeyer reaction as an alternative route.
Uses of GBL:
The industrial uses of GBL are widespread. One major usage of GBL is pyrolidones that are widely used in industrial chemicals as an intermediate in manufacturing. GBL is also used as a second major component in products such as circuit board cleaners in electronics, paint strippers and nail polish removers, due to their high solvency properties. It is used as a polyacrylonitrile, cellulose acetate, and polystyrene solvent. The production of herbicides and the production of pharmaceutics is also included in the synthesis, for example DL-methionine, piperidine, phenylbutyric acid and thiobutyric acid.
GBL is abused as a liquid often falsely presented as GHB during illicit sale. One ml of high-purity GBL is about equivalent to 2.5 g GHB 49. There are online chemical suppliers that sell GBL marketing GBL as a cleaning solvent, multi-purpose remover or
chrome polish, and as a wheel cleaner.
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